Testing for antiphospholipid antibodies at autopsy

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Testing for antiphospholipid antibodies at autopsy

Certain issues require further consideration when testing for antiphospholipid antibodies (APLAs), particularly, when the tests are to be carried out during autopsy [1–3]. First and foremost, laboratory tests must be positive on at least two different occasions, at least 12 weeks apart [4]. We have to keep in mind that APLAs may appear (transiently or persistently) in a wide variety of clinical...

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Antiphospholipid antibodies: findings at arteriography.

PURPOSE The purpose of this study was to determine the frequency and types of abnormalities at arteriography in patients with antiphospholipid antibodies (APA) and ischemic cerebrovascular events. METHODS Twenty-three patients with APA and ischemic cerebrovascular events who underwent arteriography were identified. Patients over the age of 65 years were excluded. No patients met diagnostic cr...

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Antiphospholipid antibodies.

Antiphospholipid antibodies (APLAs) are proteins that may be present in the blood and may increase your risk for blood clots or pregnancy losses. If you have a history of blood clots or recurrent pregnancy losses, you may have been tested for the presence of APLAs in your blood. The purpose of this Cardiology Patient Page is to provide information for persons with APLAs about the disorder and a...

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Antiphospholipid antibodies and stroke.

The clinical study of stroke is a recent occurrence. The clarion call awakening interest consisted of two reports that appeared during the years following World War II : the detailed description by Kubik and Adams [1) of the clinical and pathologic findings in patients with basilar artery occlusion, and C. Miller Fisher's monograph [2] directing attention to the signs and symptoms found in pati...

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Antiphospholipid antibodies and infections.

Many infections have been found to be associated with antiphospholipid antibodies (aPL), although a pathogenic role for these antibodies has not usually been obvious except in a few isolated cases. Two types of aPL have been referred to as "autoimmune" and "infectious" types. This distinction, however, has subsequently been found not to be absolute.

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ژورنال

عنوان ژورنال: Forensic Science, Medicine, and Pathology

سال: 2014

ISSN: 1547-769X,1556-2891

DOI: 10.1007/s12024-014-9528-9